281
Early26636060143106186258302382
diagnosis3085606014389134213293383463525569632
Diagnosis113410130128101140203273342412467506561
is17301013012898153
the19181013012898168230
process218310130128130177246309371425480
of269810130128129176
recognizing290910130128107169231301370441479542580651720
a366510130128122
disease382210130128130168223285347402464
and432110130128122192262
evaluating461810130128122191254293363425463502572642
the52951013012899169230
individual8511254012839110179219288327397467530568
biological145412540128108148217256327396435497560598
and208612540128102172242
social23631254012893163225264327365
characteristics276312540128100171234279342404442505550589644683722784839
of363612540128110157
a382712540128101
subject,39631254012893163233273335397435470
which446712540128140210249311381
includes48831254012878148211249319389452505
a542412540128101
targeted8511497012839102149218280319381451
medical134314970128109169239279341404443
examination,18201497012868137200308345415478517557626697732
interpretation25871497012846115155218263333381442481544582620690760
of33821497012876122
the35391497012845114177
results,37501497012852115168239277317371406
and41911497012867137207
their44321497012845114177216262
generalization47301497012874137207269316378416455518579618657728797
into8511738012839110148219
a11051738012861
definitive12011738012870133180218287327365405474537
diagnosis17721738012870109171241311382436474529
[6].23371738012846117164198
Early11341981012694164227265335
diagnosis15051981012684122193262341410465503558
aims21011979012869107217270
to24071979012846116
identify25591979012844115177247285325371441
patients30341979012877139178218281350389443
with351819790128102140180249
symptoms38031979012861132240308348418528580
as44191979012869123
early45781979012869131178217288
as48991979012869124
possible50591979012877147202256295365404467
to8512220012839110
provide9962220012886133202271311381443
them14742220012855124187296
with181922200128102140180250
the21042220012855126188
best23272220012885148202241
chance26032220012879148211280343405
of30422220012887134
successful32102220012871141203266328382437483553592
treatment.38372220012854102164226264374434504544579
When446622200128133201264334
treatment48362220012855102164226265375435505545
is54162220012854108
delayed8512463012870133172234304365435
or13212463012871119
unavailable,14752463012871142204274337375413476545584646681
certain21912463012863126172211274312383
diseases26092463012871110164227289342405460
have31042463012871133202265
a34042463012863
lower35022463012840111213275321
survival38582463012855125173242280351413452
rate,43452463012848110148211246
more462824630128109177224286
treatmentrelated49492463012840871502122503604204905298512704012847109148211249312381
complications,126727040128117188297365405443506568606646715786840875
and217727040128117188257
higher247027040128123163232303365412
treatment29172704012894140202264303411472542582
costs.353527040128117186241279334370
Early394027040128140202249287357
diagnosis433127040128126165228297367437491530585
improves49512704012893203270318388459520574
prognosis8512945012870117188257327397452490545
by143229450128103174
acting16392945012897159198236307377
on205029450128105174
endpoints,22602945012897166236306376415485524578614
and29092945012896165235
is31802945012872127
therefore33422945012872142205252314361430477539
an39152945012897167
important41172945012873183251321368407469538578
public473029450128104173244282321384
health514929450128103166228266306375
strategy851318601285594141202241304373444
in13283186012839109
all14733186012863102140
settings16483186012855116155194233303373428
[8].21103186012847118166200
Screening11343428012878140187249312381420490561
is17303428012868123
a18883428012892
different201534280128100139186233295341402472512
strategy25623428012883123170231270333402472
than30683428012868139202272
early33763428012892153200237308
diagnosis.371734280128100140202273342413467506560596
It43483428012876115
is44993428012868122
defined465734280128100161208247317380450
as51423428012892146
the53233428012869139201
presumptive8513670012870117180233304413481521560630693
identification15793670012873144206276314354400439501563602640711781
of239536700128106152
an25823670012898168
unrecognized278636700128105175222284346415485556594657719788
disease361036700128104144198261323377439
in40843670012875145
a42643670012898
seemingly43963670012890153215325361432503541612
healthy,504136700128106168231270309379450483
asymptomatic8513911012862117188296364404474584644683722785
population16713911012872142212282321384421461531601
using23073911012872126165235305
tests,26473911012840103157196250285
examinations,29673911012864135196306344414477515553624694748783
or37853911012872119
other39393911012871110181242289
procedures42633911012871118189250313383453500562616
that49143911012841111174211
can51613911012864127196
be53923911012871133
quickly8514152012870141179242311351421
and13054152012882152223
easily15634152012881144197238277347
applied19434152012882153224262301363433
to24124152012857127
the25754152012858127190
target28004152012858120167237299338
population.31734152012888159228298337400438476547617652
A386041520128120
screening40154152012873136183245307376415486555
program46064152012889136205275322384493
should51324152012874144215285324393
include8514394012839110172210280351412
all129843940128113152190
the15244394012889158221
essential178043940128113167221284353393431494532
components,234743940128113183293360431502563634672727763
from31454394012896143212322
inviting34994394012889160231270309348418487
the40224394012889159221
target42784394012889152199268331370
population468343940128119190259329368430469508578648
to53674394012887157
providing8514636012870117188257296366405474545
access14324636012862123185248301356
to18244636012837108
effective19674636012863109155217279318357428489
treatment2492463601283985148209248358418488528
for30554636012847116163
individuals32534636012839108179218287327396467529568622
diagnosed39104636012871109171241311381435498567
with451246360128102140179249
the47964636012839109171
disease.50024636012871109163226288342404439
Compared11344877012894164273341404451513583
to17534877012866136
early19244877012890152199237308
diagnosis,22654877012898138201270339410464502557593
screening28934877012882146193255317386426496565
for34944877012874144191
cancer37204877012890152221284346393
is41484877012865120
a43044877012889
separate44284877012882144214276322384423486
and49494877012890159229
more521448770128136204251313
complex8515119012862133242310350412483
public13695119012895165235274312375
health17795119012895158220258298367
strategy21825119012880119166228266329398469
that26845119012865136198236
requires29565119012873135204274313359422476
additional34685119012888157227266305344414484546584
resources,40885119012873135188259329376437499554590
infrastructure,47135119012863134181227289344382429498561599670717778812
and8515360012862133202
coordination.10895360012874144213261330369439501539578648718754
The18785360012897166228
WHO215353600128132232333
recommends25205360012859121183254365473533603674729
implementing32845360012851160228268330440500570609649719789
screening41095360012865127174236299368407477547
programs46915360012882129198268315377487539
only52655360012882153191262
when85156020128101171234304
their11915602012853123186224271
effectiveness14975602012878124171232295334372442505574636690745
has22785602012884147200
been25145602012885148210279
demonstrated,28295602012884147256324394449488535597635698768804
when368356020128101171233303
resources40225602012861124177252322369431492546
are46045602012878124187
sufficient48265602012870139186233271334372435504543
to54055602012853123
cover8515843012862133202265312
the11985843012846115178
target14115843012846109156225287325
population,17725843012877146217287325388427465535606641
when245558430128101171234303
there27935843012846116178225287
are31165843012869115177
facilities33285843012853116178217257295334373436489
for38535843012853124170
confirming40585843012869139209256295341449486557627
diagnoses47215843012877116179248319388442505558
and53155843012869139209
providing8516085012870117188257296366405474545
treatment,14326085012863110173234273383443513552588
and20546085012888158228
when231760850128128197260329
the26826085012863133196
prevalence29136085012895142204273335374437506569631
of35796085012895142
the37576085012863134196
disease39886085012896135189251314367429
is44526085012865119
high46076085012896134204275
enough49176085012887157227297367437
to53896085012864135
justify8516326012839109164203242289359
screening12436326012855117164226289358398467537
[2].18156326012847118165199
WHO113465690128133232334
illustrates1503656901285090129199254292340402440503556
the20956569012850120183
differences23136569012880120167213275322384453516578632
between29806569012882144183285346409478
screening34936569012865128175237300369407478547
and40766569012874143214
early43256569012873135182220291
diagnosis46496569012883122185254324394448487542
in52266569012850120
its5382656901284988142
Guidelines85168100128101171210280343382420490553607
(2017,14946810012868137207277347382
2020)19126810012891160230301348
with229568100128122161199269
the26006810012860129192
following28276810012868138177216286388426496567
figure34296810012868106177246293356
«How38206810012891192262363
screening42186810012876139185246308378417487557
differs48106810012892130177224286333387
from52326810012868115185295
early8517051012862125171210281
diagnosis11657051012871110173242312382436476530
based17307051012870132186249318
on20837051012870140
the22597051012838108171
appearance24657051012863131201264326373434504567628
of31297051012870117
symptoms»)32807051012854125234301341411522574645691
Figure40067051012878117188258305367
3.44077051012870106
Healthy9397610011087140192225259319381
Abnormal16037610011087147207267307399453486
Pre-invasive23967610011067107160200233293353406453486546599
Invasive3337761001104098158213259292352406
Advanced40447610011087147207260319372425485
cancer45597610011054107166221274313
Death490376100110235288340373433
The27247315012886155218
appearance29767315012863133202265327373435505567630
of36427315012870117
symptoms37947315012853124231299339409520572