198
Dispensary8516010126101140195273336414467537600670
observation1555601012670149202265327396467513551621700
of2288601012671118
patients2441601012678147194233295373419474
with29496010126101141187265
bronchial3248601012678140210289351429467537576
asthma3858601012670125172249366435
Basic851882012894156211249312
Terms1198882012886147194303355
and1589882012862132203
Definitions18288820128101162209248318357396435505575630
Bronchial8511168012894140211280343412452514552
asthma143911680128108162201271381441
(BA)19151168012893187288334
is22861168012885140
a246111680128108
heterogeneous260411680128116179218279326396466529598660730800855
disease,349411680128116154209272333388451486
characterized401511680128107177240286348410448511558596659721790
by484111680128116187
chronic506111680128109179226295365404466
inflammation8511353012839110157195257367475535574613684755
of16401353012876122
the17971353012845114177
airways,20081353012868106153255316387439475
the25181353012844115177
presence27301353012874122184237300370432494
of32601353012874121
respiratory34171353012852113168237277324385424494541611
symptoms40621353012860131239307346417527579
such46761353012861131194264
as49751353012868122
attacks51321353012868106145208269338392
of8511537012870117
breathing10031537012873120182244283352392461531
difficulty,15691537012873112159205244307376414454523558
wheezing,216515370128101171233296358396467536572
chest27721537012865134197251290
tightness,3097153701284280150220259329391445500535
and36661537012866136205
cough,39071537012864134204274344380
which432415370128101171210273342
vary47001537012874137182253
over49861537012873144207253
time5273153701284381191251
and8511723012862133202
in10891723012839108
intensity,12321723012839109148211280334374412483516
and17831723012862132203
manifest202017230128109170240280327389443482
together25381723012837108178240278352413460
with303317230128102140178248
variable33171723012870132178217280349387450
airflow38021723012863102148194233303405
obstruction.42411723012870140195233281351413452490561630666
The8512008012886155218
heterogeneity11042008012892154192255302371441503574635674713783
of19212008012891138
BA209420080128115217
is23452008012860115
manifested249620080128130190261300347410464503565635
by31662008012891161
various33622008012891154201240309380434
disease38312008012892130184247309363426
phenotypes,42922008012891161223293362402473541604658694
many502120080128130190260331
of53872008012891138
which85121930128101171210273342
can12292193012862124193
be14582193012870132
identified16252193012838109171241279319365404466536
in21972193012839108
routine23412193012846116186224264333396
clinical27722193012863100140209248311373411
practice.32182193012870117180242280320381444479
Status37322193012878117179217287342
asthmaticus41102193012862115155224334395434473535605659
is4805219301283993
an49332193012862133
episode51012193012862131170225294364426
of8512379012870117
acute10032379012863125194234295
respiratory13332379012847110164234272319382420490537608
failure19742379012847109148187257304366
due23742379012870140203
to26122379012839108
an27562379012862131
exacerbation29222379012863133195257319365435498536575645715
of36722379012870119
BA.38272379012893195229
Asthma85126630128101155195265374434
exacerbation132026630128121191254316379425495557595635704774
-213126630128105
episodes227026630128121190229283353424486540
of284526630128128175
progressive305426630128129175244314362423477531571641703
shortness379126630128113183253300339408471525579
of440426630128129176
breath,461426630128129175237300338408444
cough,509126630128121191261330401437
wheezing,85128490128101171234296358396467537572
or14582849012870117
chest16102849012863131194248286
tightness1932284901283977146217255325388442497
requiring24642849012847109178249287334372443512
changes30122849012862131194263333395450
to34982849012837108
the36412849012838108171
usual38462849012870124195257295
treatment4177284901283985147209247356417487527
regimen.47392849012847109178218327387458493
Bronchial8513134012894140211280343412452514552
hyperresponsiveness143931340128871582262893363834454995696397097648028729341005106611211175
-26523134012864
a27513134012880
functional28663134012865135206268307345415484547586
disorder34883134012886126180250297367429475
manifested401631340128109169240279326389443482544614
by46653134012888159
episodes48573134012880150190244314384447500
of53933134012888135
bronchial8513320012870117188257320389428490529
obstruction14143320012870140195234281350413453492561632
in20803320012839110
response22253320012847109163232303373428489
to27503320012839108
stimuli2893332001285593133242310349388
that33163320012839109171210
are35623320012861108170
safe37673320012855116163225
for40273320012847116163
a42253320012863
healthy43223320012871133195234273343413
person.47693320012870132179234304374410
Sensitization8513604012878140211265304343382444506545584653724
is16103604012867122
an17673604012891160
increased19613604012868137200247309372425488557
sensitivity25543604012881144213268307345385454494532603
to31903604012867138
a33633604012890
specific34883604012882152215277315362401464
allergen/type39863604012891128168231276346408477517555626694757
of47783604012899145
allergens,49583604012891129168230277347409479533568
determined8513789012870133172234281390426497560630
by151637890128104175
skin17243789012889159198268
testing20273789012872135190228267337407
and/or24703789012895165235274344391
an28953789012897166
elevated30963789012897135197267330368431500
level36313789012872135205267306
of397237890128104150
specific41583789012887158221282320367406468
IgE;46613789012881150236275
clinically49703789012897136175244284347408447485556
significant851397501285594164233273320358421483552592
and14783975012861131201
latent17143975012839102140202272310
sensitization20603975012854117187241280321359422484522562631701
are27963975012863110172
distinguished.30013975012870110164203242312382452490545615678747782
Phenotype8514259012878148211280351389460528591
-14784259012857
the15704259012848119181
set17864259012864127166
of19864259012881127
an21484259012873143
organism's23254259012881128197260329368423532555610
characteristics29704259012873143206252314375414477524562617655694756811
that38164259012849119181219
develop40714259012879142211274313382452
as45594259012872126
a47204259012873
result48274259012857120173244282322
of51834259012881127
the53454259012849119181
interaction8514445012839110148211258320381420459529599
of14844445012870117
genetic16374445012870132201264302342403
factors20754445012846108170209279326380
and24904445012863133202
the27284445012839108171
environment.29344445012862131201240287356426536596666705741
Endotype8514730012886155226296335406474537
-14244730012846
a15054730012862
subtype16024730012855124194233304372435
of20714730012870117
a22234730012863
disease23204730012871109163226288342404
defined27604730012870132178217287349419
by32144730012870140
a33884730012862
distinct34854730012870110165203242312375413
pathobiological39334730012871132171241310381420489529598669707770832870
mechanism.483947300128109169231301364434473528638670