411
Table5106596012886148218257320
25460596012870
Global8518820128101140210280343382
10-year1267882012870140188258318381427
cardiovascular1729882012863125172242281350421483537600669708770817
risk258188201284785140209
assessment2826882012862117171233287342451512582621
scale3483882012855117178217280
Risk8511170011886122173238
Criteria112211700118167210246282340383419476
Extreme8821817471211879144180223281382439
Combination12031325011886151253317353418475511547613678
of19131325011865108
clinically2055132501185793129194230288345382418484
significant2569132501185288153217253297334391449513549
atherosclerotic3151132501185995160217260326377434470529572637673709766
cardiovascular39501325011857115158223259324390447498555620656714757
disease1473913250118661021542112693193775117129607843
with12031474011894130166230
type14661474011836103165223
217211474011865
diabetes18201474011864100158223280316374425
and/or22781474011857122188224289332
CHD26421474011887180274
or29481474011866109
two30901474011836129194
cardiovascular33171474011857116159224260326391448499556621657715758
events41071474011858122181246282333
(complications)44721474011843101165267332369405463520556592657722772816
within12031624011894130166231267331
215671624011865
years2166416240118671221812242741939159507843
in20141624011836101
a21481624011857
patient22371624011865123159196254318354
with26241624011893129165230
atherosclerotic2886162401185894160218261326376433469527570636672708767
cardiovascular36851624011858115158223259324389446497554620656714757
disease44741624011865101152209268318377
despite48831624011865123173238274310367
optimal12031773011865130166202304360396
lipid-lowering1631177301183672137174239283319384477535578615680745
therapy3240817730118371021592032603253922797174407843
and/or28721773011858124189225290333
achieved32371773011858115181217275340397463
LDL-C37321773011880173252296383
level4147177301183694160217253
≤1.444331773011871136169234
mmol/L470017730118101202265302338417
Very8823059471211894151194259
high8822767471211864100165230
-12031928011843
documented12791928011864129187252354410475511568634
atherosclerotic1946192801185793158216259324375433469527570635671707765
CVD,27431928011887180274307
clinically3083192801185793129194230288345381418486
or35991928011865108
by37401928011865132
examination39021928011857122180282316382440476512577641
results,45761928011843102152217254290341373
including12032078011836101158194259324360425489
previous17252078011866109166231267332397447
ACS,22062078011893180253285
stable2524207801185086144208244302
angina,28582078011858123189225290347379
PCI,32702078011872160203235
CABG,35392078011886180266359392
or39632078011865108
other41052078011865101165223266
arterial44032078011858101137196239275332370
surgeries,48052078011851115158223281324360417468500
stroke/TIA,1203222601185086130194259317353432475569601
peripheral18382226011864122165201266331388431490526
artery23972226011858102138195238305
disease27322226011865101152209267317376
-12032376011843
asymptomatic12792376011857108175273338374439541598634670728
documented20392376011865130187253355413477513571636
CVD27072376011887180274
by30142376011865132
imaging31762376011836138194260296361426
results:36362376011844102152217253289340376
significant4044237601185086152217253296333391448513549
plaque46262376011865101158224289346
(stenosis1203252501184394130187252317367403454
≥50%)16902525011871136201309352
by20742525011866133
angiography22372525011858122187224289354397455520584651
or29182525011865108
ultrasound,30602525011865101137180238288353418483548581
does36742525011865130187238
not39442525011865130166
include41422525011836102159196260325383
increased45572525011836102160203260319369427492
intima-media12032675011836101137173275331374476533598635692
thickness19282675011836101137194259325382433483
-12032825011843
DM12792825011893208
+15202825011873
target1625282501183694137202261297
organ19542825011865108173231295
damage,22822825011866123225281347405437
≥327522825011871135
FR,29212825011872158191
as31442825011858108
well32852825011894151188224
as35412825011858109
early36822825011858116159195262
onset39742825011865129180237274
of42812825011865108
type44222825011836102164223
146772825011865
diabetes47752825011866102159224282318375426
with12032974011894130166231
a14662974011858
duration15562974011865130173230266303368433
of20212974011865108
2021632974011865129
years23252974011867123181224274
-12033124011843
severe12793124011850108172230273331
CKD16423124011886180275
with19493124011894130166231
GFR22133124011894166253
<3024993124011873138202
ml/min/1,73273531240118101137173274310375411476508573639
m33408312401181003507309507843
-12033273011843
SCORE-212793273011872158252338417461527
for18383273011843109152
individuals20233273011836101165201266302367433490526577
aged26323273011858123180245
<29093273011873
5030153273011866131
years31783273011867122180223273
≥34853273011871
7.5%,3589327301186598162270303
for39243273011843109152
individuals41093273011836101165201266302367432490527577
aged47183273011858124181246
50-6949973273011864129174239304
years12033423011865120179222273
≥15093423011871
10%,16123423011865131238271
and19153423011858123187
SCORE-2-OR21363423011872158252340419463528571664751
for29193423011843109152
individuals31043423011836101165202266303368433491528578
aged37143423011858123180245
≥39913423011872
7040953423011866130
years42583423011867122180223274
≥45653423011871
15%46683423011865130238
-12033572011843
SGC12793572011872165252
in15633572011836101
combination16963572011857124226289325390447485521585650
with23803572011893129165230
atherosclerotic2642357201185894159216259324376433469527570635671707764
CVD34403572011886181274
or37473572011864108
with38873572011894130166231
FR41513572011872158
High8824427471211894130194259
-12033727011843
significantly1279372701185086151216252295332389447512548584651
pronounced19603727011865108173237303368433492549614
FR26063727011872159
-27973727011844
CH28743727011886181
˃30873727011873
831933727011865
mmol/L329137270118101202267303340419
and/or37423727011858123188224288332
LDL41063727011879174253
˃43923727011873
4.94497372701186597163
mmol/L469437270118100201265302338417
and/or12033877011858122187223288331
BP15673877011886158
≥17593877011871
180/11018623877011865129195231296361426
mmHg232138770118101202295360
-12034025011843
CHD12794025011886180273
without15854025011893129165231296361397
FR20144025011872160
-12034175011843
DM12794175011893208
without15204175011893129165230296361397
target1949417501183694137202259297
organ22784175011865108174231296
damage,26064175011865123225281346404436
DM30764175011893208
≥33184175011871
1034214175011865130
years35834175011866121180223274
or38904175011865108
with40304175011894130166232
FR42944175011872159
-12034324011843
moderate127943240118100165230287331388424482
CKD17944324011887180274
with21004324011894130167232
GFR23654324011894166252
30-5926504324011864129173238304
ml/min/1.73298843240118100135171273309374410475507572638
m3365943240118101165
-12034474011843
SCORE-212794474011872158252338417461527
for18384474011843109152
individuals20234474011836101165201266302367433490526577
aged26324474011858123180245
<29094474011873
5030154474011866131
years31784474011867122180223273
≥34854474011871
2.53589447401186598162
<37844474011873
7.5%,3889447401186597162270303
for42254474011843109152
individuals44104474011836101166202266302367433491527577
aged50194474011858123180245
50-6912034624011865130173238302
years15384624011867122180223273
≥18454624011871
519484624011865
<20454624011874
10%,21524624011865129237270
and24554624011858123187
SCORE-2-OR26754624011872158252339419463528571664752
for34594624011844109153
individuals36444624011836101166202266302367432490526577
aged42534624011858123180245
≥45324624011871
7046354624011865130
years47974624011867123181224274
≥51044624011871
7.55207462401186598162
<15%12034773011873138203311
Moderate88255234712118115180245302345403439497
-12034928011843
young12794928011866128194259323
patients16354928011865122158195253318354404
(type2071492801184480147209268
123714928011866
diabetes24694928011865101159224281317375425
younger29264928011868130196261325383426
than33854928011837101159225
3536424928011865130
years,38044928011867122180223274306
type41424928011838105167224
243994928011865
diabetes44964928011865102160224283319377427
younger49554928011868130195259324382426
than12035077011836101158223
5014585077011865130
years)16205077011868123180224275318
with19715077011893129165230
a22335077011859
duration23255077011864130173231267303368432
of27905077011865108
diabetes29325077011864100158223280316374424
<33885077011873
1034955077011865131
years36585077011866122180223274
without39645077011894130166232297361397
target4394507701183693136202260296
organ47225077011865109174232297
damage12035227011865122224281346403
and16385227011858123188
risk1858522701184581131196
factors20865227011843102160196261304355
-12035377011843
SCORE12795377011872158252338417
–17285377011867
218275377011865
for19255377011843109152
individuals21095377011836101166202267303369433491527577
aged27195377011857122180244
<29965377011873
5031035377011864129
years32655377011867122179222274
<35725377011874
2.5%,3678537701186597162270302
for40135377011843109152
individuals41985377011836100165201266302367433490526577
aged48085377011858122180245
50-6950855377011865130175240305
years12035526011865120179222273
<15095526011873
5%,16145526011865173205
and18525526011858123188
SCORE-2-OR20725526011873159254340420464529572666753
for28575526011843109152
individuals30415526011836101166202267303368434491527578
aged36525526011858122180245
≥39295526011871
7040335526011864130
years41955526011868123180223274
<45015526011873
7.5%4608552601186597162271
Low8825954471211879144238
-12035680011843
SCORE12795680011872158252338417
–17285680011867
218275680011865
for19255680011843109152
individuals21095680011836101166202267303369433491527577
aged27195680011857122180244
40-6929965680011866131174239304
years33325680011867123181224275
and36395680011859124189
SCORE-2-OR38605680011872158252339419463527571664752
for46445680011843109152
individuals48295680011836100165201266302367432489525576
aged12035829011858122180245
≥14805829011871
7015845829011864129
years17465829011868123180223275
<20535829011873
1%21585829011866174
1851602007440
IHD:9226047011041125212245
3-411976047011060100159
FC13876047011067146
angina15646047011053113174206266319
pectoris,19136047011060113167200260300333380410
unstable23536047011060120167200253313347400
angina,27836047011053112173206266319349
previous31626047011060101154213246306366413
myocardial36056047011094155213267320359419453506539
infarction,4174604701103393133187227281314347407467497
ischemic4701604701103481134194247340373427
stroke,5157604701104780120180240294323
PCI,8516206011067147189216
CABG10976206011080167247332
surgery,14596206011047107148209261300362390
angioplasty18796206011054114175208268328361415461495556
of24636206011060100
the2593620601103393146
carotid27696206011054107146206240273333
or31326206011060100
lower3262620601103494181234274
extremity35666206011053112146186240332366399461
arteries,4054620601105494128181220254307353383
carotid44676206011054107147207240273333
endarterectomy,8516364011053113173226266299352393446498531591685747775
iliac-femoral1656636401103367100154207247288341435495534588621
or2307636401106099
femoral-popliteal2436636401104093186246286340373414473533593627660694747801834
bypass.33006364011060121179233280326356
2851659607440
Atherosclerotic9226623011087120180233273333379433465519559618651685738
plaque1690662301106093147207267320
is2039662301103381
defined21506623011060114153187247300359
as25396623011054100
a26696623011053
local2752662301103393148201233
thickening3015662301103494127181241295354388448508
of35526623011060100
the3682662301103393147
wall38596623011087140172206
by40956623011060122
>50%42456623011068127187288
compared45636623011053113206266319359413473
to5066662301103393
the5189662301103394147
thickness851678201103393127180240300353399446
of13276782011060100
the1457678201103393147
vessel16346782011060113159205259292
wall19566782011087141174207
in2193678201103494
the2317678201103394147
adjacent24936782011054113146200253306365398
areas,2921678201105495148201248278
or32296782011060100
as3359678201105399
a34886782011053
local3571678201103393146200233
area3834678201105494146200
of40646782011060100
the4194678201103393146
vascular43706782011060114160213273306360400
wall47996782011087141174207
with50366782011087120154214
a52806782011053
CIM8516941011080121225
>1.511066941011068128158218
mm13546941011093186
that1571694101103393146180
protrudes17816941011060100159193233293354407453
into2264694101103393127187
the2481694101103494147
lumen2658694101103393187240300
3851717207440
Myocardial92271990110107168224279331371431464519551
infarction,1503719901103494134187226280312346406467497
unstable20307199011061121168201254314347401
angina,24617199011053112173205265319349
intermittent2840719901103393126180220312346380413467526559
claudication,3429719901105487140200260293347400432466526586616
transient4075719901103473127186233266319379414
ischemic4519719901103380133193246339373426
attack/ischemic851735801105386120173226285319352399453512565658692745
stroke.1626735801104780120180240293323
with19807358011086121154214
ezetimibe.22247358011054106160193226320354414467497