251
Clinical8516010126101140179258296358429467
and1352601012670149227
Laboratory1613601012694164242312375444490560623692
Diagnostics.23416010126101139209279358427481528567630683719
The851839012886155218
incubation1104839012862131194263334397435473544613
period1753839012891154201240309379
is2168839012861115
6-142318839012893142211281
days.2635839012892155225278314
The29848390128107177240
severity3259839012876139209271317356395465
of3758839012892139
the3932839012862133194
clinical4161839012885124163232272335396435
picture4631839012893131194232303349411
directly5077839012893131179241303341380450
depends8511080012870133202265335405459
on134510800128108178
the15581080012876147209
duration180210800128108178225286325365434504
of234110800128108155
incubation.25311080012877146209278348411450488558628664
The322910800128123193256
most352010800128147215270309
severe38651080012891154224286333395
"fulminant"42951080012894140210250360396467530599638695
form50311080012885154201310
of537410800128108155
tetanus8511321012839102141203273342396
runs128313210128102172241295
its16141321012894132186
course183613210128117186256303357419
within229013210128156195233304342412
24-36273813210128125194243312382
hours.315613210128123194264311364400
The359113210128140210273
classic389913210128116155217271325364427
triad43601321012893140179241311
described470613210128124187240303350388458520590
by533213210128124194
Hippocrates85115630128101140210280351412459522561623677
remains15641563012856117226286325396451
the20501563012847118181
main227515630128109169208279
criterion25891563012872119157195258305342413483
for31071563012856125172
the33131563012848119182
clinical35301563012870109148218257320382420
diagnosis39851563012879118181250320390444483537
of45571563012880127
tetanus47191563012847110148210279350404
to51591563012848117
this53121563012847118156211
day.8511805012870133203237
671207409146
Trismus8512048012694156195249366443497
–13842046012870
spasmodic14902046012868139202255365433503543605
clenching21302046012877116178248310380419489559
of27232046012886133
the28902046012854124187
jaws,31112046012854116216270305
caused34512046012878140209264326396
by38822046012885156
spasm40712046012870139202257366
of44702046012886133
the46372046012854124186
masticatory487220460128110170224264303366428466536583653
muscles.85122870128109177232295334397452487
671255709146
A85125290128101
pained9872529012870132171242304373
("sardonic")13962529012847104157220267336407476516577635682
smile21122529012854164201240303
resulting24502529012847109164234273311350420490
from2975252901284794164273
spasm32812529012856126189242352
of36662529012870117
the38182529012839109172
facial40252529012847109170209272310
muscles.437125290128109178233295333396450485
671279909146
Convulsive8512771012894164233304374413467506576639
arching15252771012887134195265304374444
of20052771012893141
the21812771012864133196
spine24122771012880149189258321
(opisthotonos)27682771012872141211250305343413484522593662732787834
is36372771012863118
associated37912771012887140195265328365428467529599
with442627710128125163203272
a47342771012887
sharp48562771012880150213259329
tonic52202771012863134203243304
contraction8513012012862133202242289351412451490559630
of15153012012870117
the16683012012839108171
striated1874301201285392140178239278341410
muscles232030120128109176232294333396450
of28053012012870117
the29573012012838109170
body,31633012012870139210280314
varying35113012012870133180250287358429
in39753012012838108
degree41173012012870133202249312373
of45253012012870117
severity.46773012012855118187250295334373443477
Prodromal8513254012878125195265312382492552591
phenomena14773254012875145207276346456516586649
can21623254012867129198
include23963254012843113176213283354416
nagging28463254012875137207277315386455
pain33373254012873136175245
or36173254012874121
muscle377732540128110177232295333396
twitching42083254012842144182221283353392462532
in47753254012842113
the49233254012843113175
area51343254012865112174237
of54063254012873120
the8513495012839110172
wound.106234950128101171240310381416
General151634950128101163233295342404442
malaise,199734950128109170209272311366428463
difficulty24953495012873113160206245307376415454525
changing30533495012866136199269339378448519
body36073495012872143212283
position,39233495012874144199238277316385456492
walking,445134950128102164203273313382452487
insomnia,49743495012841112166236345413453515550
yawning,8513737012870131232302341412482518
disorders14043737012873112167236283352415462515
and19553737012866135205
pain21963737012872135174243
in24753737012842112
the26223737012843112175
throat28323737012842112159229291330
when320037370128101171233304
swallowing,35393737012858160222260298369470508578648683
back42583737012873135197267
pain,45603737012874137174244280
a48753737012865
feeling49753737012850112175214253323393
of54033737012873121
tightness851397801283978148219257327390443498
in13853978012855125
the15453978012856125188
chest,17683978012879148211264304338
and21413978012879149220
awkwardness23963978012879180252354416461532601664718773
when321939780128102171234304
moving357539780128110177248287357427
the40373978012856125188
head42603978012887150211281
also45773978012878117172241
precede48543978012886133196257319388451
the53403978012856125187
clinical8514220012862101141210249312374412
picture12984220012871109172210280327389
of17224220012870117
the18744220012838108171
disease20794220012870109164226288342405
by25194220012870140
several26934220012855117187250296359397
days31254220012870133202255
[10].34154220012847119190237271
The8514461012886155218
first110444610128129167215269308
reliable144744610128128190229268331400439501
symptom198344610128136207315383423493603
is261844610128122177
trismus.283044610128122169207261371439495530
Almost339544610128184222332400455494
simultaneously,392444610128137175285353392432494564625695765820859929963
difficulty492244610128152191238285323386455494533603
swallowing8514702012855156218257296366468505576646
–153247020128125
dysphagia169347020128122193246316386449518557620
–234847020128124
and250847020128116186255
a279947020128116
sardonic295047020128108171217287356427465528
smile351347020128109218255294357
appear.390547020128116185256318380427462
These440247020128139209272326389
three48264702012892162208271333
early519447020128116179225263334
symptoms8514945012855125234302341412521574
in14604945012840110
combination16064945012862132242310349420481520560630699
are23414945012862109171
characteristic25474945012862131194241303364403466512551605644683745
only33274945012870140179249
of36104945012870117
tetanus.37624945012839102141203273343397432
Subsequently,8515186012878148219273336405474537607646684755788
rigidity16745186012873112182221291330369439
of21465186012897144
the23255186012865134197
neck25575186012895158219290
muscles,288151860128135203258321360422476512
tonic34285186012864134204242305
tension37685186012864127196251289359430
of42325186012896142
the44105186012863134197
muscles464151860128135203258321360422476
of51515186012897144
the53295186012865134196
back,8515427012870133195264300
abdomen,11865427012870139210279389449519555
arms,17765427012870117226278314
and21255427012870140210
legs23705427012846109178233
sets26385427012862125162217
in.28905427012847117152
As308554270128101154
a32745427012870
result,33795427012855117171240280318354
at37685427012870108
the39115427012846117180
slightest41255427012862101139210279319381435475
external46345427012871140179242288358421459
stimuli51285427012862100139249317356396
(auditory,8515668012847109179249289327397444514547
visual,14345668012871111166236298337373
tactile),18425668012839102164202241280343389424
tetanic23015668012841103141204273313375
(or27115668012848118168
clonic)29155668012863102171241280343389
convulsions33395668012864134204275344383438476547617671
occur,40455668012872134196267313348
causing44285668012864127197251290360430
the48935668012841111174
body51025668012871141211282
to54175668012841110
assume8515911012862117172242351411
a129759110128116
"rigid,144959110128110157196267307376412
column-like189659110128116185224294403471520559599668731
state266259110128108147210247310
with300759110128155194232303
arching334559110128116163225295333404473
of385459110128123171
the40605911012891162224
spine431959110128108178217287349
into47035911012893163201272
a501059110128116
curve516159110128116185233303364
(opisthotonos)"8516152012847117188226280320389459498568639708762810867
[10].17536152012847116186233267