112
years,851596012870131193240294330
the1216596012849120183
diagnosis1434596012879119180251320390445483539
of2007596012879127
pertussis2169596012879142189228297351406445499
can2703596012873136205
be2943596012881142
confirmed3121596012872141212259297344453513584
based3740596012881144197260329
on4104596012881151
a4290596012873
fourfold4398596012856126197243290360399468
increase4902596012849119182228290352407468
in5406596012849119
antibody851839012862133172211280351420491
titers137583901284988127189236291
over1701839012878148211258
time199483901284886196256
after2285839012872119158220267
10-142587839012880149199269339
days,2961839012878141211264300
or3296839012879126
upon3457839012880149219290
detection3782839012878141179242304342381451521
of4338839012880127
IgA4499839012856126228
and4761839012872142212
high5008839012878118187258
IgG5302839012854125225
titers851108001283978117180226280
in11661080012840109
individuals13101080012839108178218287327396466529568622
vaccinated19661080012870132194256295365428466529598
more259910800128109177224287
than29211080012839109172241
532001080012870
years33061080012870130192239294
ago.36351080012863133202238
671135009146
Conduct8511321012894164233304374436474
a136113210128110
double150613210128118187258328366429
bacteriological197013210128117179242280342389427498536606676715778840878
examination288313210128110180242351389460523561599670739
of36611321012870116
sputum381213210128102172243281351460
or430513210128118166
mucus450613210128159226289359414
from49561321012894141210320
the53091321012886157220
posterior8511563012870141195233296343382452499
pharyngeal13851563012874144207254324392463526588626
wall205115630128101163202241
or23281563012874122
nasopharynx24851563012876137192262331402465510580649720
in32401563012843114
patients33901563012874137175214277346385440
suspected38651563012859130184253316378416479548
of44491563012874121
having46061563012875137207246315386
pertussis50281563012874137184222292346400440494
and8511805012862133202
presenting108918050128120166228283345415453493563632
with175718050128151190228298
a208918050128113
cough223718050128112181252321391
for26631805012897166213
no291218050128119189
more313618050128158225273335
than35061805012889160223292
14-21383318050128119190241310379
days.424818050128119181251304339
Bacteriological462218050128144206268307370417455526564634704743806868906
examination8512046012862133195305341412475514552622692
is15792046012865120
carried17352046012889151198245283345415
out21862046012896166205
before24262046012897159206275322385
the28462046012865135197
start30782046012882121182229268
of33822046012896143
antibiotic35602046012890159198237307346416455494556
therapy.41512046012865135198245306376447480
For466620460128105175222
diagnostic49242046012897135198267338408462501539602
purposes,8512287012870141188257327382444498534
the14202287012848117180
test16352287012849111165204
should18742287012865134204274313383
be22922287012880142
performed24682287012881143190236305353462522592
twice30962287012849151189251314
daily34452287012879142181219290
or37682287012881128
every39312287012872142205250321
other42852287012881120190252298
day46182287012881143213
in48642287012850121
the50192287012849119182
early52362287012872134181219289
stages851252901285594157226289342
of12292529012870116
the13802529012839108171
disease15862529012870109164225288342404
(no20252529012847116186
later22472529012837100138201248
than25302529012839108171240
the28062529012839108171
3rd30102529012870118188
week323225290128101163225296
of35632529012870117
illness).3715252901283878116186249302357404439