143
1754097556011060120
Pathogenesis2860597010873132172239299359412479532579612659
After851852011087127159213253
HIV1136852011087128213
infection138085201103595135189241274308368428
enters1838852011057116150203244290
the215885201103696149
bloodstream,233785201106295155215275322356396449503596626
viremia299385201106296135189283316370
lasts339285201103689136169216
from363885201104282141235
23903852011062
to399685201103696
44122852011063
weeks.4217852011087141195254301331
There4580852011073133187226280
are489085201105696149
a5069852011056
number5156852011062122215275328368
of8511059011060100
cells9811059011056109142175222
in1233105901103797
the1360105901103797151
human15411059011063123216270330
body19011059011063123183244
that2173105901103696150183
have23861059011064117176231
receptors2646105901104497150203263296356396443
for31191059011043103144
HIV32961059011087127213
(the3539105901104376136189
presence37581059011063104158203257316371423
of42111059011063103
a43441059011058
target4432105901103891131190244276
receptor).4738105901104497151204263297357397436466
These52371059011074134188234288
are851126601105393146
CD4+102612660110157244304371
lymphocytes,142712660110110172263323383443497559590643690720
CD8+217712660110157244304372
lymphocytes,257812660110110171262322382442496558589642689719
dendritic332812660110136190249309349382416449503
cells,386012660110130183216249296326
monocytes,421612660110170230290350404467498553599629
eosinophils,487512660110130190236270330390450510543577624654
megakaryocytes,8511473011093147207260319372412474531586648677732778808
neurons,168914730110101154214255315375422452
microglia,217114730110134168221261321381413446500529
and27301473011095155215
spermatozoa.29751473011087147201240334387421481534595648678
CD4+368314730110120207267335
lymphocytes40471473011074135226286346408461522553607653
have473014730110101154214267
the50271473011074134188
main524514730110134187221281
receptors851168001104093146198258291351393439
for13201680011056116156
HIV-1.150616800110102144229269329359
The18961680011089149203
attachment21291680011068101135188242302395448508542
of27011680011075115
the28471680011049109162
virus30391680011075109150210257
particle33261680011076129169202235289322375
is3732168001104995
carried38571680011069123163203235289349
out42361680011076136169
by44351680011077138
the46011680011049109163
gp12047941680011076135195255315
protein.51401680011076116176209262295355385
Penetration8511886011067120180233266306359392425486546
into1427188601103393126187
the1644188601103393146
cell18201886011054106139173
is2023188601103380
carried21331886011053107146186218272332
out24951886011060120153
by26781886011060122
the2828188601103393147
gp4130051886011060119179239
genome32741886011061113173233326382
of36861886011060100
the3816188601103393146
virus.3992188601106093133193240270
The8512193011073133187
virus,1067219301106397137197243273
having13702193011064117177210270330
penetrated17292193011064117176231264304358391444504
into2263219301103797130190
CD4+24872193011080167227294
lymphocytes,2811219301103798188248308368422483514568615645
begins34862193011063116177209269316
replication.3832219301104497156190223277330363397457517547
The44122193011074134187
more46322193011093153193247
active49082193011057110142176236289
CD4+52302193011080167227295
cells8512401011053106139172219
are,11002401011076116169198
the13282401011056116170
higher15282401011082115177236289329
the18872401011056116169
process20872401011083123183236289335381
of24982401011083123
virus26512401011083116156216263
reproduction.29442401011062116175216276336397450483516576636666
CD4+364024010110103190250318
cell39872401011076129162195
activators42122401011076129162195256310343403443490
(tumor4732240101106296156249309349
necrosis51112401011082136188228288335368415
factor,851260801104093146179239279309
interleukin-6,1190260801103494127181220254307366426460520561621651
colony18712608011054114147209269330
stimulating2228260801104881115209269302356388422482542
factor2799260801104194148181241281
of31102608011061101
granulocytes/macrophages)324126080110611021562162763093694224845155686156487427958488899491009106911221182123612821322
provide45932608011061101161221254314367
an49902608011054114
increase5134260801103494147188241294340394
in851281501103393
viral974281501106094134187220
replication.Interferon12242815011040931521862192733263593924525125425836426757287688098639029621022
and22762815011054113173
transforming2479281501103373127187233273333373466499560621
growth3130281501106099159246279339
factor3499281501104093146179239279
inhibit3808281501103393153187247280313
viral4152281501106093133186219
replication.4401281501104094154187221274327360393454514544
The8513123011073133187
life1067312301103367107160
cycle12563123011054116166199254
of15393123011060100
HIV16693123011087129214
after1913312301105392126180219
penetration21623123011060114173226259300354386419480540
into2732312301103393126187
the2949312301103393146
body:31253123011060120180241272